Beijing Nuoxuan Kangle Biological Science and Technology Co.ltd.

If you are retarded due to auxin deficiency, you can use auxin therapy.

Growth hormone, also known as human growth hormone (hGH), is a peptide hormone banned in sports. It is usually used in the treatment of dwarfism. It has the function of anabolism, which can increase muscle mass and promote bone growth in childhood and adolescence, and strengthen tendons and enlarge internal organs. Athletes use illegal growth hormone mainly to strengthen their muscles and increase their strength in order to gain competitive advantage.

Pharmacokinetics has been reported in the literature that subcutaneous or intramuscular injection has the same effect in two ways. Subcutaneous injection usually leads to a higher serum GH concentration than intramuscular injection, but the concentration of IGF-1 is consistent. GH absorption is usually slow, plasma GH concentration usually reaches its peak after 3-5 hours of administration, and the clearance of the half-life is generally 2-3 hours; GH is cleared through the liver and kidney, and adults are faster than children. The unmetabolized GH, which is directly removed from the urine, is very small.

HGH growth hormone secretion decreases with age:

The effect of autologous feedback cycle

When the body IGF-l decreases, it sends signals to the pituitary gland to produce more hGH, which decreases with age.

Secretion of HGH

It is regulated by the effects of two kinds of hormones secreted by the hypothalamus Hypothalamus: (a) Growth Hormonereleasing Hormone (GHRH): it stimulates hGH secretion. The concentration of the whole life is the same. Somatostatin (b) Somatostatin (SKIF): inhibition of secretion, there is a decrease in band sex every day, that is, the peak band of hGH secretion, but this Somatostatin increases with age. And the increase of hGH secretion gradually weaken the secretion of hGH.

The dosage used to promote the growth of children varies from person to person. The recommended dose is 0.1-0.15IU/kg weight / day, once a day, subcutaneous injection, for 3 months to 3 years, or a doctor's order.

The recommended dose for severe burns is 0.2-0.4IU/kg body weight / day, once daily, subcutaneous injection, the course of treatment is usually about 2 weeks